| W | = | Weekend Gross |
| T | = | Total Gross |
|
| 1 | Beverly Hills Chihuahua
W: $29M T:$29M |
| 2 | Eagle Eye
W:$17.7M T:$54.6M |
| 3 | Nick and Norah's Infinite Playlist
W:$12M T:$12M |
| 4 | Nights in Rodanthe
W:$7.36M T:$25.1M |
| 5 | Appaloosa
W:$5.01M T:$5.57M |
| 6 | Lakeview Terrace
W:$4.5M T:$32.1M |
| 7 | Burn After Reading
W:$4.08M T:$51.6M |
| 8 | Fireproof
W:$4.07M T:$12.5M |
| 9 | An American Carol
W:$3.81M T:$3.81M |
| 10 | Religulous
W:$3.5M T:$3.52M |
